If you have moderate to severe pain that radiates from your lower back and buttock down into the back of your leg, you may have sciatica (also called lumbar radiculopathy) – a painful condition that affects millions of Americans.
Sciatica is often caused by a bulging disc in the lower back pressing against the sciatic nerve - a nerve that begins in the lower back and extends down the back of each leg. This is why sciatica pain often feels like it “travels” down the back of one leg. Sciatica pain varies from person to person. Sometimes it is a sharp or shooting pain, while for others it can feel like tingling, numbness or weakness.
If you’ve been struggling with sciatica leg pain for at least 2 months, you may qualify for the SERENITY CM Clinical Study, now being offered at select US centers. The study is for an investigational, non-steroid, non-opioid treatment designed to relieve sciatica pain going down one leg. Participants in the SERENITY CM Study will receive all study-related care at no cost.
Currently, there are no FDA-approved treatments specifically for people with long-lasting sciatica leg pain. The SERENITY CM Study is evaluating a new investigational treatment for sciatica leg pain. It involves a single injection that does not contain steroids or opiods, but rather uses clonidine, a pain reliever and anti-inflammatory medication. In addition, the investigational treatment is an extended-release formulation, designed to provide long-term pain relief.
The SERENITY CM Study is currently being offered at select doctors’ offices throughout the US. If you qualify and choose to join the study, you will be seen by a local physician and will receive all study-related care at no cost.
As part of the study you will meet with your study doctor and team regularly over a 12-month period to evaluate your progress and discuss your experiences (7 follow-up visits after your treatment). You will also receive a modest payment for each visit you complete.
See If You Qualify
If you are 18 - 70 years old and have been struggling with sciatica leg pain for at least 2 months, you may qualify for the SERENITY CM Clinical Study. The study is for an investigational new treatment designed to provide long-term relief of sciatica leg pain. It involves a single injection that does not contain steroids or opioids.
To see if you might qualify, and to get connected with your local study center to learn more, please complete the questionnaire below.